4.7 Article

Multicomponent synthesis of spiroisoxazolines

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 70, Issue 21, Pages 8395-8399

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo051181w

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A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.

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