4.7 Review

Neurobiology of decision making: A selective review from a neurocognitive and clinical perspective

Journal

BIOLOGICAL PSYCHIATRY
Volume 58, Issue 8, Pages 597-604

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.biopsych.2005.06.004

Keywords

anticipation; anxiety; choice selection; development; motivation; schizophrenia

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we present a temporal map of key processes that occur during decision making, which consists of three stages: 1) formation of preferences among options, 2) selection and execution of an action, and 3) experience or evaluation of an outcome. This framework can be used to integrate findings of traditional choice psycbology neuropsychology, brain lesion studies, and functional neuroimaging. Decision making is distributed across various brain centers, which are differentially active across these stages of decision making. This approach can be used to follow developmental trajectories of the different stages of decision making and to identify unique deficits associated with distinct psychiatric disorders.

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