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Surfing with the tunicates into the post-genome era

Journal

GENES & DEVELOPMENT
Volume 19, Issue 20, Pages 2407-2411

Publisher

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.1365805

Keywords

ascidians; Ciona; gene networks; genomics; morphogenesis

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This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the postgenome era, but in many ways are leading the way to the promise of a systems-level understanding of complex processes such as notochord formation, neurogenesis, and even behavior.

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