Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 55, Issue 5, Pages 2451-2457Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01448-10
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Funding
- Spanish Ministry of Science and Innovation [FI09/00901]
- Consejo Superior de Investigaciones Cientificas (JAE-Doc)
- European Commission [LSHMCT-2008-223031, KBBE-2008-2B-227258]
- CIBERESP Network for Biomedical Research in Epidemiology and Public Health (Instituto Carlos III, Spanish Ministry of Science and Innovation) [CB06/02/0053]
- Spanish Ministry of Education [BFU2008-00995/BMC]
- RETICS research network, Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation [REIPI RD06/0008/1012]
- European VI Framework Program [LSHM-CT-2005_019023]
- Spanish Network for the Study of Plasmids and Extrachromosomal Elements (REDEEX) (Spanish Ministry of Science and Innovation) [BFU 2008-0079-E/BMC]
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The association of an IS440-sul3 platform with Tn21 class 1 integrons carried by IncI1 plasmids encoding extended-spectrum beta-lactamases (ESBLs; mainly SHV-12 and CTX-M-14) among worldwide Escherichia coli clones of phylogroups A (ST10, ST23, and ST46), B1 (ST155, ST351, and ST359), and D/B2 (ST131) is reported. An in silico comparative analysis of sul3 elements available in the GenBank database shows the evolution of sul3 platforms by hosting different transposable elements facilitating the potential genesis of IS26 composite transposons and further insertion element-mediated promoted arrangements.
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