Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 55, Issue 11, Pages 5388-5391Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.05517-11
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Funding
- Wellcome Trust
- NIHR Cambridge Biomedical Research Centre
- Sapprasithiprasong Hospital
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A 21-year survey conducted in northeast Thailand of antimicrobial resistance to parenteral antimicrobial drugs used to treat melioidosis identified 24/4,021 (0.6%) patients with one or more isolates resistant to ceftazidime (n = 8), amoxicillin-clavulanic acid (n = 4), or both drugs (n = 12). Two cases were identified at admission, and the remainder were detected a median of 15 days after starting antimicrobial therapy. Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis.
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