4.4 Article

An improved protocol for the selective hydroaminomethylation of arylethylenes

Journal

TETRAHEDRON LETTERS
Volume 46, Issue 43, Pages 7401-7405

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.08.107

Keywords

amines; catalysis; hydroaminomethylation

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The hydroaminomethylation of arylethylenes with anilines proceeds under mild conditions in the presence of [Rh(cod)(2)BF4] and dppf as catalyst system to give the corresponding branched amphetamine derivatives in good selectivity and yield. (c) 2005 Elsevier Ltd. All rights reserved.

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