4.8 Article

Facile radical trifluoromethylation of lithium enolates

Journal

ORGANIC LETTERS
Volume 7, Issue 22, Pages 4883-4885

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0517574

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[GRAPHICS] Highly basic lithium enolates are shown to be applicable to radical trifluoromethylation. The reaction is extremely fast, and the minimum reaction time is similar to 1 s.

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