4.7 Article

OXA-134, a Naturally Occurring Carbapenem-Hydrolyzing Class D β-Lactamase from Acinetobacter lwoffii

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 54, Issue 12, Pages 5372-5375

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00629-10

Keywords

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Funding

  1. INSERM [U914]
  2. Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]
  3. Universite Paris XI, Paris, France
  4. European Community [HEALTH-F3-2008-223031]
  5. Fond d'Etudes et de Recherche du Corps Medical des Hopitaux de Paris
  6. Bundesministerium fur Bildung und Forschung (BMBF), Germany, Klinische Forschergruppe Infektiologie (BMBF) [01KI0771]

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Acinetobacter lwoffii, a species whose natural habitat is the human skin, intrinsically possesses a chromosomal gene encoding a carbapenem-hydrolyzing class D beta-lactamase, OXA-134. This species may therefore constitute a reservoir for carbapenemase genes that may spread among other Acinetobacter species.

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