Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 54, Issue 9, Pages 3998-3999Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00264-10
Keywords
-
Categories
Funding
- National Natural Science Fund, China [30873127]
Ask authors/readers for more resources
The antimicrobial activities of colistin and other antibiotics against clinical Acinetobacter baumannii and the mutant prevention concentration (MPC) of colistin against multidrug-resistant A. baumannii were studied. All 70 stains tested were sensitive to colistin. The MPC range of colistin against 30 multidrug-resistant A. baumannii stains was approximately 32 to >128 mu g/ml, and the MPC at which 90% of the isolates tested were prevented (MPC(90)) exceeded 128 mu g/ml, which was much higher than the plasma concentration of colistin at the current recommended dosage. So, combination therapy for colistin treatment of A. baumannii would be prudent to slow the emergence of resistance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available