4.1 Article

Use of polynuclear metal clusters in protein crystallography

Journal

COMPTES RENDUS CHIMIE
Volume 8, Issue 11-12, Pages 1808-1814

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crci.2005.02.032

Keywords

metal clusters; macromolecular crystallography; phasing; anomalous scattering

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Application of polynuclear metal clusters for phasing X-ray crystal structures of macromolecules is discussed. Their strong isomorphous and anomalous scattering signal is particularly useful for phasing structures of large macromolecules and complexes, especially at low resolution. The popularity of the metal clusters in macromolecular crystallography is expected to grow in the future.

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