Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 54, Issue 10, Pages 4464-4466Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01318-09
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Funding
- MIUR [20077HCK77_002, 2007RXJN5N_002]
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We report the ex vivo lysogenic transfer of erythromycin and tetracycline resistance genes among group A streptococci (GAS). Of 42 susceptible strains, 69% acquired erythromycin/tetracycline resistance when infected with purified supernatants from strain m46 culture containing the phage Phi m46.1. A significant emm-type-dependent barrier to lysogenic transfer was not observed. The emm12 strains were the only strains susceptible to the lytic action of the bacteriophage preparation.
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