Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 54, Issue 2, Pages 945-949Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01316-09
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- Ontario Ministry of Health and Long Term Care, Ontario, Canada
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We describe the epidemiology of heterogeneously resistant Staphylococcus aureus (hVISA) identified in Canadian hospitals between 1995 and 2006. hVISA isolates were confirmed by the population analysis profiling-area under the curve method. Only 25 hVISA isolates (1.3% of all isolates) were detected. hVISA isolates were more likely to have been health care associated (odds ratio [OR], 5.1; 95% confidence interval [CI], 1.9 to 14.2) and to have been recovered from patients hospitalized in central Canada (OR, 3.0; 95% CI, 1.2 to 7.4). There has been no evidence of vancomycin MIC creep in Canadian strains of methicillin (meticillin)-resistant S. aureus, and hVISA strains are currently uncommon.
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