Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 54, Issue 3, Pages 1354-1357Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00899-09
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Funding
- Janssen Ortho-McNeil, Inc.
- Merck Sharp and Dohme, Inc.
- Pfizer, Inc.
- NCRR/NIH-RCMI [G12RR03051]
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During an island-wide PCR-based surveillance study of beta-lactam resistance in multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter calcoaceticus-baumannii complex isolates obtained from 17 different hospitals, 10 KPC-positive Acinetobacter isolates were identified. DNA sequencing of the bla(KPC) gene identified KPC-2, -3, and -4 and a novel variant, KPC-10. This is the first report of a KPC-type beta-lactamase identified in Acinetobacter species.
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