4.7 Article

Characterization of the Plasmid-Borne Quinolone Resistance Gene qnrB19 in Salmonella enterica Serovar Typhimurium

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 53, Issue 9, Pages 4019-4021

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00294-09

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Funding

  1. European Community Network of Excellence Med-Vet-Net Workpackages 21 [FOOD-CT-2004-506122]

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A qnrB19 gene variant, carried by an IncL/M-like plasmid, was detected in a multidrug Salmonella enterica serovar Typhimurium human strain with reduced susceptibility to ciprofloxacin. The genetic environment around the gene was fully sequenced (20 kb). A large gene cluster, containing the aph, qnrB19, and bla(SHV-12)-like resistance genes, is inserted inside a Tn3 transposon.

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