Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 53, Issue 4, Pages 1665-1666Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01447-08
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Funding
- National Institutes of Health [AI43312, AI57576]
- U.S. Public Health Service
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One hundred fifty AAC(6')-Ib-positive gram-negative isolates collected between 1981 and 1991 were examined by PCR for the presence of the aac(6')-Ib-cr variant and other plasmid-mediated quinolone resistance (PMQR) genes. None had the aac(6')-Ib-cr variant, qnrA, qnrS, qnrC, or qepA, but two strains collected in 1988 had qnrB alleles, making these the earliest known PMQR genes.
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