Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 53, Issue 8, Pages 3569-3571Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00456-09
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- Ministerio de Sanidad y Consumo of Spain [PI 050031]
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Granulocyte-macrophage colony-stimulating factor enhanced the efficacy of liposomal amphotericin B (LAMB) in a murine model of disseminated infection by Rhizopus oryzae, significantly prolonging survival and reducing tissue burden. The use of gamma interferon (IFN-gamma) alone was ineffective, and IFN-gamma combined with LAMB did not improve the results obtained with LAMB alone.
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