Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 52, Issue 9, Pages 3451-3453Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00562-08
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Funding
- MRC program of MOST/KOSEF [R13-2005-013-01000-0]
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A novel stilbene glycoside [piceid-(1 -> 6)-beta-D-glucopyranoside; PBG] from Parthenocissus tricuspidata was tested in vivo against Plasmodium berghei. PBG exhibited significant blood schizontocidal activity in a 4-day early infection, a repository evaluation, and an established infection, with a significant mean survival time comparable to that obtained with the standard drug, chloroquine (5 mg . kg(-1) . day(-1)).
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