Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 53, Issue 3, Pages 1235-1237Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00970-08
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Funding
- National Science Council (NSC) [97-3112-B-400-005]
- National Health Research Institutes [MG-097-PP12, CL-096-PP02]
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The DNA sequences of two IncHI2 plasmids, pEC-IMP and pEC-IMPQ, from metallo-beta-lactamase-producing Enterobacter cloacae clinical isolates were determined. The two conjugative plasmids are almost identical, but pEC-IMPQ carries an additional segment containing an orf513 (ISCR1), a truncated 3' conserved sequence, and a qnrB2. Comparative analyses provide support for the proposed ISCR1-mediated gene mobilization.
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