4.7 Article

Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum β-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 52, Issue 5, Pages 1790-1793

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01440-07

Keywords

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Funding

  1. FIC NIH HHS [D43TW006592, D43 TW006592] Funding Source: Medline
  2. NIAID NIH HHS [T32AI007333, R01 AI070896, T32 AI007333, R01AI070896] Funding Source: Medline

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An outbreak of cephalosporin-resistant Klebsiella pneumoniae occurred in a neonatal intensive care unit in Sao Paulo, Brazil. Of the 10 pulsotypes identified during the outbreak and follow-up periods, nine produced CTX-M-2 or its new variant CTX-M-59 and one produced SRV-5. bla(CTX-M-2/59) genes were located on closely related plasmids that were transferable.

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