Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 6, Issue 11, Pages 862-871Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1745
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Funding
- NIGMS NIH HHS [R01 GM061074] Funding Source: Medline
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Binary fission of many prokaryotes as well as some eukaryotic organelles depends on the FtsZ protein, which self-assembles into a membrane-associated ring structure early in the division process. FtsZ is homologous to tubulin, the building block of the microtubule cytoskeleton in eukaryotes. Recent advances in genomics and cell-imaging techniques have paved the way for the remarkable progress in our understanding of fission in bacteria and organelles.
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