Journal
EUROPEAN JOURNAL OF RADIOLOGY
Volume 56, Issue 2, Pages 171-178Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ejrad.2005.03.020
Keywords
PET; SPECT; low-grade glioma; radionuclide imaging
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Low-grade gliomas (LGG) account for 30-40% of all gliomas and are primarily treated with surgery. Since both timing and use of other oncological treatments in LGG are a matter of controversy, there has been a constantly increasing demand to characterize these often slowly growing neoplasms with functional imaging methods, such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT). PET and SPECT yield information on growth rate and heterogeneity of LGG and are especially useful in follow-up since metabolic changes tend to precede structural changes detected with structure-based imaging methods. Furthermore, for planning of LGG surgery or radiotherapy coregistration of functional images with CT and MRI is invaluable. This is increasingly performed with a new generation of hybrid scanners with integrated PET or SPECT and CT. (C) 2005 Elsevier Ireland Ltd. All rights reserved.
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