Journal
PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 24, Issue 11, Pages 1021-1023Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.inf.0000183938.33484.bd
Keywords
respiratory syncytial virus; monoclonal antibody; Synagis; palivizumab
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To evaluate the safety and immunogenicity of palivizumab, 55 children who received palivizumab in the IMpact-RSV trial received 5 monthly doses of 15 mg/kg palivizumab (Synagis) during the subsequent year. The single child with an antipalivizumab titer of > 1/40 had no associated serious adverse events and had expected serum palivizumab trough concentrations. Second year palivizumab prophylaxis was safe and well-tolerated.
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