Journal
NATURE METHODS
Volume 2, Issue 11, Pages 829-831Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH797
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Accurate measurement of telomeric 3'-overhang (G-tail) lengths is essential for investigation of the biological effects of telomere dysfunction. G-tail telomere hybridization protection assay (Gt-tetomere HPA) has the advantages of being simple to perform, accurate and highly sensitive for G tails as short as 20 nucleotides. Furthermore, Gt-tetomere HPA is specific and quantitative for human G tails, and can be used to assay cell lysates as well as genomic DNA.
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