Journal
ANNUAL REVIEW OF PLANT BIOLOGY
Volume 60, Issue -, Pages 93-114Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev.arplant.043008.092114
Keywords
quantitative trait; genetic variation; network analysis; regulation; genetical genomics
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Funding
- National Science Foundation [DBI0642481]
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Scientific inquiries in fields ranging from ecology to plant breeding assess phenotypic variation within a plant species either to explain its presence or utilize its consequences. Frequently this natural genetic variation is studied via mapping quantitative trait loci (QTLs); however, elucidation of the underlying molecular mechanisms is a continuing bottleneck. The genomic analysis of transcripts as individual phenotypes has led to the emerging field of expression QTL analysis. This field has begun both to delve into the ecological/evolutionary significance of this transcript variation as well as to use specific eQTLs to speed up our analysis of the molecular basis of quantitative traits. This review introduces cQTL analysis and begins to illustrate how these data can be applied to multiple research fields.
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