Journal
FEMS MICROBIOLOGY LETTERS
Volume 252, Issue 2, Pages 309-313Publisher
OXFORD UNIV PRESS
DOI: 10.1016/j.femsle.2005.09.013
Keywords
Chaetomium globosum; chaetoviridin; Magnaporthe grisea; Puccinia recondita
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The Chaetomium globosum strain F0142, which was isolated from barnyard grass, showed potent disease control efficacy against rice blast (Magnaporthe grisea) and wheat leaf rust (Puccinia recondita). Two antifungal substances were purified from broth from this organism and identified as chaetoviridins A and B. Chaetoviridin A exhibited higher antifungal activity than chaetoviridin B against plant pathogenic fungi both in vitro and in vivo. Treatment with chaetoviridin A at 62.5 mu g/mL suppressed the development of rice blast and wheat leaf rust by over 80%. The molecule also exhibited moderate control of tomato late blight, resulting in 50% control following the application of 125 mu g/mL chaetoviridin A. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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