Related references
Note: Only part of the references are listed.Neurofibromatosis type 1 (NF1) and pheochromocytoma: prevalence, clinical and cardiovascular aspects
Laura Zinnamosca et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2011)
Neurofibromatosis-1 Heterozygosity Increases Microglia in a Spatially and Temporally Restricted Pattern Relevant to Mouse Optic Glioma Formation and Growth
Grant W. Simmons et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Phase I trial of pegylated interferon-α-2b in young patients with plexiform neurofibromas
R. I. Jakacki et al.
NEUROLOGY (2011)
The ecology of brain tumors: lessons learned from neurofibromatosis-1
W. W. Pong et al.
ONCOGENE (2011)
Nf1-/- Schwann Cell-Conditioned Medium Modulates Mast Cell Degranulation by c-Kit-Mediated Hyperactivation of Phosphatidylinositol 3-Kinase
Shi Chen et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Molecular and Cellular Mechanisms of Learning Disabilities: A Focus on NF1
C. Shilyansky et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 33 (2010)
Cyclic AMP Suppression Is Sufficient to Induce Gliomagenesis in a Mouse Model of Neurofibromatosis-1
Nicole M. Warrington et al.
CANCER RESEARCH (2010)
Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level
Christopher B. Franco et al.
CELL STEM CELL (2010)
Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells
Karl Staser et al.
CURRENT OPINION IN HEMATOLOGY (2010)
Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner
Da Yong Lee et al.
GENES & DEVELOPMENT (2010)
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
Elisabeth A. Lasater et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model
Maria Demestre et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
Dominico Vigil et al.
NATURE REVIEWS CANCER (2010)
An Illustrative Case of Neurofibromatosis Type 1 and NF1 Microdeletion
L. A. Praxedes et al.
MOLECULAR SYNDROMOLOGY (2010)
Cell of Origin and Microenvironment Contribution for NF1-Associated Dermal Neurofibromas
Lu Q. Le et al.
CELL STEM CELL (2009)
Microarray Analyses Reveal Regional Astrocyte Heterogeneity with Implications for Neurofibromatosis Type 1 (NF1)-Regulated Glial Proliferation
Tu-Hsueh Yeh et al.
GLIA (2009)
Unravelling the genetic basis of variable clinical expression in neurofibromatosis 1
Audrey Sabbagh et al.
HUMAN MOLECULAR GENETICS (2009)
Ras Dependent Paracrine Secretion of Osteopontin by Nf1 +/- Osteoblasts Promote Osteoclast Activation in a Neurofibromatosis Type I Murine Model
Hume Li et al.
PEDIATRIC RESEARCH (2009)
Translation of the Philadelphia chromosome into therapy for CML
Brian J. Druker
BLOOD (2008)
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells
Andrew S. McDaniel et al.
BLOOD (2008)
Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin
Mateusz Kolanczyk et al.
BMC MEDICINE (2008)
Induction of abnormal proliferation by nonmyelinating Schwann cells triggers neurofibroma formation
Huarui Zheng et al.
CANCER CELL (2008)
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells
Jianqiang Wu et al.
CANCER CELL (2008)
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells
Nancy M. Joseph et al.
CANCER CELL (2008)
Increased c-Jun-NH2-Kinase Signaling in Neurofibromatosis-1 Heterozygous Microglia Drives Microglia Activation and Promotes Optic Glioma Proliferation
Girish C. Daginakatte et al.
CANCER RESEARCH (2008)
Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/- and c-kit-Dependent Bone Marrow
Feng-Chun Yang et al.
CELL (2008)
Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning
Yijun Cui et al.
CELL (2008)
How Does the Schwann Cell Lineage Form Tumors in NF1?
Steven L. Carroll et al.
GLIA (2008)
Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway
Elisabeth A. Lasater et al.
HUMAN MOLECULAR GENETICS (2008)
Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis
Stephen J. Galli et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2008)
Somatic mutation analysis in NF1 cafe au lait spots reveals two NF1 hits in the melanocytes
Sofie De Schepper et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
New developments in mast cell biology
Janet Kalesnikoff et al.
NATURE IMMUNOLOGY (2008)
Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
Stephen J. Galli et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1
Jincheng Yan et al.
HUMAN MOLECULAR GENETICS (2008)
Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1
Nicole M. Warrington et al.
CANCER RESEARCH (2007)
Molecular dissection of isolated disease features in mosaic neurofibromatosis type 1
Ophelia Maertens et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Tumor microenvironment and neurofibromatosis type I: connecting the GAPs
L. Q. Le et al.
ONCOGENE (2007)
Congenital pseudarthrosis of the tibia:: analysis of the histology and the NF1 gene
Akio Sakamoto et al.
JOURNAL OF ORTHOPAEDIC SCIENCE (2007)
Further evidence of the increased risk for malignant peripheral nerve sheath tumour from a Scottish cohort of patients with neurofibromatosis type 1
A. McCoughan et al.
JOURNAL OF MEDICAL GENETICS (2007)
Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth
Girish C. Daginakatte et al.
HUMAN MOLECULAR GENETICS (2007)
K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells
Waleed F. Khalaf et al.
JOURNAL OF IMMUNOLOGY (2007)
Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies
Jessica J. Hawes et al.
NEUROGENETICS (2007)
An absence of cutaneous neurofibromas associated with a 3-bp inframe deletion in Exon 17 of the NF1 gene (c.2970-2972 delAAT): evidence of a clinically significant NF1 genotype-phenotype correlation
M. Upadhyaya et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Hyperactivation of p21ras and PI3K cooperate to after murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions
Feng-Chun Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Comprehensive NF1 screening on cultured Schwann cells from neurofibromas
Ophelia Maertens et al.
HUMAN MUTATION (2006)
Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes
Manish Aghi et al.
CANCER RESEARCH (2006)
Nf1± mast cells induce neurofibroma like phenotypes through secreted TGF-β signaling
Feng-Chun Yang et al.
HUMAN MOLECULAR GENETICS (2006)
Mast cells can enhance resistance to snake and honeybee venoms
Martin Metz et al.
SCIENCE (2006)
Double inactivation of NF1 in tibial pseudarthrosis
DA Stevenson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells
Fang Li et al.
HUMAN MOLECULAR GENETICS (2006)
Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells
Amy M. Munchhof et al.
HUMAN MOLECULAR GENETICS (2006)
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas
BC Widemann et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Distinct role of macrophages in different tumor microenvironments
CE Lewis et al.
CANCER RESEARCH (2006)
Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation
Y Zhu et al.
DEVELOPMENT (2005)
Loss of the Nf1 tumor suppressor gene decreases Fas antigen expression in myeloid cells
K Hiatt et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1
GA Mashour et al.
CLINICAL CANCER RESEARCH (2004)
Neurofibromatosis 1: closing the GAP between mice and men
B Dasgupta et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2003)
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1(+/-) mast cells
FC Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Mouse models of neurofibromatosis type I: bridging the GAP
RM Costa et al.
TRENDS IN MOLECULAR MEDICINE (2003)
Somatic NF1 mutation spectra in a family with neurofibromatosis type 1: Toward a theory of genetic modifiers
V Wiest et al.
HUMAN MUTATION (2003)
Lymphoproliferative defects in mice lacking the expression of neurofibromin:: functional and biochemical consequences of Nf1 deficiency in T-cell development and function
DA Ingram et al.
BLOOD (2002)
Therapy for plexiform neurofibromatosis in children with neurofibromatosis 1: An overview
RJ Packer et al.
JOURNAL OF CHILD NEUROLOGY (2002)
Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation
ML Bajenaru et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Neurofibromas in NF1: Schwann cell origin and role of tumor environment
Y Zhu et al.
SCIENCE (2002)
Malignant peripheral nerve sheath tumours in neurofibromatosis 1
DGR Evans et al.
JOURNAL OF MEDICAL GENETICS (2002)
Hyperactivation of p21ras and the hematopoietic-specific Rho GTPase Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro
DA Ingram et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
Y Zhu et al.
GENES & DEVELOPMENT (2001)
Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells
KK Hiatt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells
GA Mashour et al.
ONCOGENE (2001)
Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1
JL Rutkowski et al.
HUMAN MOLECULAR GENETICS (2000)
Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells
FC Yang et al.
IMMUNITY (2000)
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo
DA Ingram et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
NF1 microdeletion breakpoints are clustered at flanking repetitive sequences
MO Dorschner et al.
HUMAN MOLECULAR GENETICS (2000)
Share Paper
