Journal
ANNUAL REVIEW OF NEUROSCIENCE, VOL 36
Volume 36, Issue -, Pages 271-294Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-neuro-062012-170433
Keywords
attention; interneurons; pyramidal cells; oscillation; synchrony
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Funding
- BBSRC [BB/F021399/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/F021399/1, BBS/B/09325] Funding Source: Medline
- Medical Research Council Funding Source: Medline
- Wellcome Trust Funding Source: Medline
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Muscarinic signaling affects attention, action selection, learning, and memory through multiple signaling cascades, which act at different timescales and which alter ion channels in cell type-specific manners. The effects of muscarinic signaling differ between cortical layers and between brain areas. Muscarinic signaling adds flexibility to the processing mode of neuronal networks, thereby supporting processing according to task demands. This review outlines possible scenarios to describe how it contributes to cellular mechanisms of attention and how it affects channeling of information in different neuronal circuits.
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