Journal
ANNUAL REVIEW OF MICROBIOLOGY, VOL 66
Volume 66, Issue -, Pages 285-303Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-micro-092611-150120
Keywords
bacterial behavior; bacterial motility; signaling; transmembrane receptors; history of science
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Funding
- NIGMS NIH HHS [R01 GM029963, R37 GM029963, GM29963] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM029963, R37GM029963] Funding Source: NIH RePORTER
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This review focuses on the early years of molecular studies of bacterial chemotaxis and motility, beginning in the 1960s with Julius Adler's pioneering work. It describes key observations that established the field and made bacterial chemotaxis a paradigm for the molecular understanding of biological signaling. Consideration of those early years includes aspects of science seldom described in journals: the accidental findings, personal interactions, and scientific culture that often drive scientific progress.
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