☆ 4.6 Article

Probing dipeptide trans/cis stereochemistry using pH control of thiopeptide analogues, and application to the PepT1 transporter

ORGANIC & BIOMOLECULAR CHEMISTRY (2005)

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Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 3, Issue 22, Pages 4038-4039

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b513274f

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Categories

Chemistry, Organic

Funding

  1. Wellcome Trust Funding Source: Medline

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The stereochemistry of thiodipeptides of proline [e.g. Ala-psi[CS-N]-Pro] can be controlled using pH, allowing the trans-preference for substrates of the peptide transporter PepT1 to be confirmed.

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