4.5 Article

Ti-mediated synthesis of aminocyclopropyl-substituted carbohydrates

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2005, Issue 23, Pages 5084-5088

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200500406

Keywords

carbohydrates; cyanides; cyclopropanes; Grignard reagents; titanium

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Carbohydrates bearing aminocyclopropyl moieties were conveniently prepared from the corresponding nitriles by titanium-mediated addition of Grignard reagents. A wide range of protective groups are tolerated. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.

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