A general synthesis of N-aryl- and N-alkyl-2-aminobenzoxazoles

An efficient and practical synthetic procedure is described for the preparation of a variety of N-substituted aryl- and alkyl-2-aminobenzoxazoles. This new method offers broad utility and provides desired products in good to excellent yield. The title compounds are formed in a one-pot, two step reaction sequence that is safe and operationally straightforward. (c) 2005 Elsevier Ltd. All rights reserved.