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JOURNAL OF IMMUNOLOGY (2006)
IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
Toshiyuki Owaki et al.
JOURNAL OF IMMUNOLOGY (2006)
Interferons α and λ inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics
Tobias Marcello et al.
GASTROENTEROLOGY (2006)
Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs
Stefanie Kunz et al.
EXPERIMENTAL DERMATOLOGY (2006)
General nature of the STAT3-activated anti-inflammatory response
Karim C. El Kasmi et al.
JOURNAL OF IMMUNOLOGY (2006)
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
Andre Boonstra et al.
JOURNAL OF IMMUNOLOGY (2006)
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
Jason R. Chan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex
Sung Il Yoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Expression and regulation of IL-22 in the IL-17-producing CD4+T lymphocytes
Yeonseok Chung et al.
CELL RESEARCH (2006)
Resolution of a chronic viral infection after interleukin-10 receptor blockade
Mette Ejrnaes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
Spencer C. Liang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Interleukin-22: A novel T- and NK-cell derived cytokine that regulates the biology of tissue cells
Kerstin Wolk et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes
Sean E. Doyle et al.
HEPATOLOGY (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats
He Chang et al.
JOURNAL OF IMMUNOLOGY (2006)
Ultraviolet B light stimulates interleukin-20 expression by human epithelial keratinocytes
David W. C. Hunt et al.
PHOTOCHEMISTRY AND PHOTOBIOLOGY (2006)
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Jason S. Stumhofer et al.
NATURE IMMUNOLOGY (2006)
Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis
Yu-Hsiang Hsu et al.
ARTHRITIS AND RHEUMATISM (2006)
Prominent production of IL-20 by CD68+/CD11c+ myeloid-derived cells in psoriasis:: Gene regulation and cellular effects
Frank Wang et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Transforming growth factor-β induces development of the TH17 lineage
PR Mangan et al.
NATURE (2006)
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
D Yen et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes:: a potential role in psoriasis
Kerstin Wolk et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
IFN-γ suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins
Xiaoyu Hu et al.
IMMUNITY (2006)
Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response
S Fujita et al.
BLOOD (2006)
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
S Brand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4+ T cells
John Shoemaker et al.
JOURNAL OF IMMUNOLOGY (2006)
Interactions among the components of the interleukin-10 receptor complex
CD Krause et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
M Veldhoen et al.
IMMUNITY (2006)
Interleukin-10 in the pathophysiology of inflammatory bowel disease: Increased serum concentrations during the recovery phase
Keiichi Mitsuyama et al.
MEDIATORS OF INFLAMMATION (2006)
The two faces of interleukin 10 in human infectious diseases
Jean-Louis Mege et al.
LANCET INFECTIOUS DISEASES (2006)
Distal enhancer elements transcribe intergenic RNA in the IL-10 family gene cluster
EA Jones et al.
JOURNAL OF IMMUNOLOGY (2005)
IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
S Brand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis
K Otkjaer et al.
BRITISH JOURNAL OF DERMATOLOGY (2005)
Possible relations between the polymorphisms of the cytokines IL-19, IL-20 and IL-24 and plaque-type psoriasis
S Koks et al.
GENES AND IMMUNITY (2005)
Biological activity of interleukins-28 and-29: Comparison with type I interferons
A Meager et al.
CYTOKINE (2005)
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
NC Rogers et al.
IMMUNITY (2005)
Expression of interleukin-22 in rheumatoid arthritis - Potential role as a proinflammatory cytokine
H Ikeuchi et al.
ARTHRITIS AND RHEUMATISM (2005)
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
CM Hawrylowicz et al.
NATURE REVIEWS IMMUNOLOGY (2005)
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
K Boniface et al.
JOURNAL OF IMMUNOLOGY (2005)
CD25+CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
T Barthlott et al.
INTERNATIONAL IMMUNOLOGY (2005)
Regulation of IL-10 gene expression in Th2 cells by Jun proteins
ZY Wang et al.
JOURNAL OF IMMUNOLOGY (2005)
Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts
A Andoh et al.
GASTROENTEROLOGY (2005)
IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues
AL Gurney
INTERNATIONAL IMMUNOPHARMACOLOGY (2004)
A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells
S Dillon et al.
JOURNAL OF IMMUNOLOGY (2004)
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
MG Netea et al.
JOURNAL OF IMMUNOLOGY (2004)
Polymorphisms in the interleukin-20 gene: relationships to plaque-type psoriasis
K Kingo et al.
GENES AND IMMUNITY (2004)
Cutting edge: IL-26 signals through a novel receptor complex composed of IEL-20 receptor 1 and IL-10 receptor 2
F Sheikh et al.
JOURNAL OF IMMUNOLOGY (2004)
IL-6 and IL-10 induction from dendritic cells in response to Mycobacterium tuberculosis is predominantly dependent on TLR2-mediated recognition
S Jang et al.
JOURNAL OF IMMUNOLOGY (2004)
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
M de la Rosa et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Regulatory T cells and mechanisms of immune system control
A O'Garra et al.
NATURE MEDICINE (2004)
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
WT Huang et al.
JOURNAL OF INFECTIOUS DISEASES (2004)
IL-19 induced Th2 cytokines and was up-regulated in asthma patients
SC Liao et al.
JOURNAL OF IMMUNOLOGY (2004)
Combined haplotype analysis of the interleukin-19 and-20 genes:: relationship to plaque-type psoriasis
S Koks et al.
GENES AND IMMUNITY (2004)
An essential function for the nuclear receptor ROR gamma t in the generation of fetal lymphoid tissue inducer cells
G Eberl et al.
NATURE IMMUNOLOGY (2004)
Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses
JF Zhu et al.
NATURE IMMUNOLOGY (2004)
Interleukin-10 and related cytokines and receptors
S Pestka et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
PL Vieira et al.
JOURNAL OF IMMUNOLOGY (2004)
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
S Radaeva et al.
HEPATOLOGY (2004)
Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells
ML Nagalakshmi et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2004)
Cutting edge: Different toll-like receptor agonists instruct dendritic cells to induce distinct th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-fos
S Agrawal et al.
JOURNAL OF IMMUNOLOGY (2003)
Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice
E Kanters et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology
SC Higgins et al.
JOURNAL OF IMMUNOLOGY (2003)
Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein 8 and 5 in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages
YW Liu et al.
JOURNAL OF IMMUNOLOGY (2003)
IFN-α induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3
L Ziegler-Heitbrock et al.
JOURNAL OF IMMUNOLOGY (2003)
IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity
T Kopp et al.
JOURNAL OF IMMUNOLOGY (2003)
Interleukin-10 therapy - Review of a new approach
K Asadullah et al.
PHARMACOLOGICAL REVIEWS (2003)
Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3
L Dumoutier et al.
BIOCHEMICAL JOURNAL (2003)
cAMP-induced interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation
S Brenner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
Mycobacteria target DC-SIGN to suppress dendritic cell function
TBH Geijtenbeek et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Epidermal overexpression of interleukin-19 and-20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine A or calcipotriol
J Romer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)
Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20
L Liu et al.
BLOOD (2003)
IL-28, IL-29 and their class II cytokine receptor IL-28R
P Sheppard et al.
NATURE IMMUNOLOGY (2003)
IFN-lambda s mediate antiviral protection through a distinct class II cytokine receptor complex
SV Kotenko et al.
NATURE IMMUNOLOGY (2003)
A novel host-parasite lipid cross-talk - Schistosomal lyso-phosphatidylserine activates Toll-like receptor 2 and affects immune polarization
D van der Kleij et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Interleukins 19, 20, and 24 signal through two distinct receptor complexes - Differences in receptor-ligand interactions mediate unique biological functions
JP Novak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
A Sing et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
IL-19 induces production of IL-6 and TNF-α and results in cell apoptosis through TNF-α
YC Liao et al.
JOURNAL OF IMMUNOLOGY (2002)
Microbial recognition via toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering
AD Edwards et al.
JOURNAL OF IMMUNOLOGY (2002)
Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line - Pathways that are shared with and distinct from IL-10
D Lejeune et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Crystal structure of recombinant human interleukin-22
RAP Nagem et al.
STRUCTURE (2002)
Cutting edge: Immune cells as sources and targets of the IL-10 family members?
K Wolk et al.
JOURNAL OF IMMUNOLOGY (2002)
Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: Central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response
AK Yi et al.
JOURNAL OF IMMUNOLOGY (2002)
In vitro generation of interleukin 10-producing regulatory CD4+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
FJ Barrat et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon γ
H Tilg et al.
GUT (2002)
Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2
M Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types
L Dumoutier et al.
JOURNAL OF IMMUNOLOGY (2001)
Regulatory T cells in the control of immune pathology
KJ Maloy et al.
NATURE IMMUNOLOGY (2001)
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
WF Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site
K Josephson et al.
IMMUNITY (2001)
Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity
SV Kotenko et al.
JOURNAL OF IMMUNOLOGY (2001)
Reversing lipopolysaccharide toxicity by ligating the macrophage Fcγ receptors
JS Gerber et al.
JOURNAL OF IMMUNOLOGY (2001)
Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells
G Schaefer et al.
JOURNAL OF IMMUNOLOGY (2001)
Identification of the functional interleukin-22 (IL-22) receptor complex -: The IL-10R2 chain (IL-10Rβ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
SV Kotenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Interleukin 20: Discovery, receptor identification, and role in epidermal function
H Blumberg et al.
CELL (2001)
IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes
L Dumoutier et al.
GENES AND IMMUNITY (2000)
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
B Oppmann et al.
IMMUNITY (2000)
Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
MH Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
G Gallagher et al.
GENES AND IMMUNITY (2000)
IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3
M Tone et al.
JOURNAL OF IMMUNOLOGY (2000)
Increased resistance to systemic candidiasis in athymic or interleukin-10-depleted mice
D Tavares et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
Antibiotic therapy attenuates colitis in interleukin 10 gene-deficient mice
KL Madsen et al.
GASTROENTEROLOGY (2000)
Design and analysis of an engineered human interleukin-10 monomer
K Josephson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri
A Knappe et al.
JOURNAL OF VIROLOGY (2000)
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages
HD Brightbill et al.
JOURNAL OF IMMUNOLOGY (2000)
Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9
L Dumoutier et al.
JOURNAL OF IMMUNOLOGY (2000)
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