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The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation
JC Nolz et al.
CURRENT BIOLOGY (2006)
Multiplexed absolute quantification for proteomics using concatenated signature peptides encoded by QconCAT genes
Julie M. Pratt et al.
NATURE PROTOCOLS (2006)
Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts
IC Schneider et al.
JOURNAL OF CELL BIOLOGY (2005)
Detection and measurement of alternative splicing using splicing-sensitive microarrays
K Srinivasan et al.
METHODS (2005)
Silencing of microRNAs in vivo with 'antagomirs'
J Krützfeldt et al.
NATURE (2005)
A protein interaction network of the malaria parasite Plasmodium falciparum
DJ LaCount et al.
NATURE (2005)
The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer
P Tolar et al.
NATURE IMMUNOLOGY (2005)
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
W Kolch
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Modeling T cell antigen discrimination based on feedback control of digital ERK responses
G Altan-Bonnet et al.
PLOS BIOLOGY (2005)
Towards a proteome-scale map of the human protein-protein interaction network
JF Rual et al.
NATURE (2005)
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
G Campi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The Ezh2 methyltransferase complex: actin up in the cytosol
JC Nolz et al.
TRENDS IN CELL BIOLOGY (2005)
Plasmon light scattering in biology and medicine: new sensing approaches, visions and perspectives
K Aslan et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2005)
A human protein-protein interaction network:: A resource for annotating the proteome
U Stelzl et al.
CELL (2005)
Accurate multiplex polony sequencing of an evolved bacterial genome
J Shendure et al.
SCIENCE (2005)
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT
AT Willingham et al.
SCIENCE (2005)
Peripheral blood gene expression profiling in rheumatoid arthritis
FM Batliwalla et al.
GENES AND IMMUNITY (2005)
Evidence for ectopic neurotransmission at a neuronal synapse
JS Coggan et al.
SCIENCE (2005)
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
J Liou et al.
CURRENT BIOLOGY (2005)
Stochastic reaction-diffusion simulation with MesoRD
J Hattne et al.
BIOINFORMATICS (2005)
Genomewide analysis of the host response to malaria in Kenyan children
MJ Griffiths et al.
JOURNAL OF INFECTIOUS DISEASES (2005)
STIM1, an essential and conserved component of store-operated Ca2+ channel function
J Roos et al.
JOURNAL OF CELL BIOLOGY (2005)
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
V Pascual et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
High-throughput mapping of a dynamic signaling network in mammalian cells
M Barrios-Rodiles et al.
SCIENCE (2005)
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications
DS Kirkpatrick et al.
METHODS (2005)
Whole-genome patterns of common DNA variation in three human populations
DA Hinds et al.
SCIENCE (2005)
Development of a model for microphysiological simulations - Small nodes of Ranvier from peripheral nerves of mice reconstructed by electron tomography
GE Sosinsky et al.
NEUROINFORMATICS (2005)
Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome
R Reghunathan et al.
BMC IMMUNOLOGY (2005)
Automatic generation of cellular reaction networks with Moleculizer 1.0
L Lok et al.
NATURE BIOTECHNOLOGY (2005)
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
S Cabantous et al.
NATURE BIOTECHNOLOGY (2005)
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
G Meister et al.
RNA (2004)
ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation
S Faure et al.
NATURE IMMUNOLOGY (2004)
A physical and functional map of the human TNF-α NF-κB signal transduction pathway
T Bouwmeester et al.
NATURE CELL BIOLOGY (2004)
A map of the interactome network of the metazoan C-elegans
SM Li et al.
SCIENCE (2004)
Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation
K Bodour et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
MicroRNAs modulate hematopoietic lineage differentiation
CZ Chen et al.
SCIENCE (2004)
Stochastic simulation of chemical reactions with spatial resolution and single molecule detail
SS Andrews et al.
PHYSICAL BIOLOGY (2004)
Self-assembling protein microarrays
N Ramachandran et al.
SCIENCE (2004)
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
PL Ross et al.
MOLECULAR & CELLULAR PROTEOMICS (2004)
Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making
A Yates et al.
JOURNAL OF THEORETICAL BIOLOGY (2004)
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry
JEP Syka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cellware - a multi-algorithmic software for computational systems biology
P Dhar et al.
BIOINFORMATICS (2004)
Feedback control of T-cell receptor activation
C Chan et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2004)
Bioconductor: open software development for computational biology and bioinformatics
RC Gentleman et al.
GENOME BIOLOGY (2004)
The complexity of complexes in signal transduction
WS Hlavacek et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
A protein interaction map of Drosophila melanogaster
L Giot et al.
SCIENCE (2003)
Intracellular phospho-protein staining techniques for flow cytometry: Monitoring single cell signaling events
PO Krutzik et al.
CYTOMETRY PART A (2003)
Gene expression profile in multiple sclerosis patients and healthy controls:: identifying pathways relevant to disease
R Bomprezzi et al.
HUMAN MOLECULAR GENETICS (2003)
E-cell 2: Multi-platform E-Cell simulation system
K Takahashi et al.
BIOINFORMATICS (2003)
Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites
D Chaussabel et al.
BLOOD (2003)
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
SA Gerber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation
C Kesmir et al.
JOURNAL OF THEORETICAL BIOLOGY (2003)
Cellerator: extending a computer algebra system to include biochemical arrows for signal transduction simulations
BE Shapiro et al.
BIOINFORMATICS (2003)
Genetics of gene expression surveyed in maize, mouse and man
EE Schadt et al.
NATURE (2003)
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
L Bennett et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Mass spectrometry-based proteomics
R Aebersold et al.
NATURE (2003)
Structural evidence for feedback activation by Ras-GTP of the Ras-specific nucleotide exchange factor SOS
SM Margarit et al.
CELL (2003)
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
I Stefanová et al.
NATURE IMMUNOLOGY (2003)
Turnover rates of B cells, T cells, and NK cells in simian immunodeficiency virus-infected and uninfected rhesus macaques
RJ De Boer et al.
JOURNAL OF IMMUNOLOGY (2003)
Protein chip technology
H Zhu et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2003)
Affinity purification-mass spectrometry - Powerful tools for the characterization of protein complexes
A Bauer et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Microarrayed recombinant allergens for diagnosis of allergy
C Harwanegg et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2003)
Sequence requirements for micro RNA processing and function in human cells
Y Zeng et al.
RNA (2003)
Activated TCRs remain marked for internalization after dissociation from pMHC
D Coombs et al.
NATURE IMMUNOLOGY (2002)
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
SC Bunnell et al.
JOURNAL OF CELL BIOLOGY (2002)
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
SE Ong et al.
MOLECULAR & CELLULAR PROTEOMICS (2002)
Genetic dissection of transcriptional regulation in budding yeast
RB Brem et al.
SCIENCE (2002)
T cell receptor signaling precedes immunological synapse formation
KH Lee et al.
SCIENCE (2002)
Human macrophage activation programs induced by bacterial pathogens
GJ Nau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Stereotyped and specific gene expression programs in human innate immune responses to bacteria
JC Boldrick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Autoantigen microarrays for multiplex characterization of autoantibody responses
WH Robinson et al.
NATURE MEDICINE (2002)
Modeling the heart - from genes to cells to the whole organ
D Noble
SCIENCE (2002)
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
J Delon et al.
IMMUNITY (2001)
The plasticity of dendritic cell responses to pathogens and their components
Q Huang et al.
SCIENCE (2001)
The art of the probable: System control in the adaptive immune system
RN Germain
SCIENCE (2001)
High-throughput yeast two-hybrid assays for large-scale protein interaction manning
AJM Walhout et al.
METHODS (2001)
Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading
WS Hlavacek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Synaptic pattern formation during cellular recognition
SY Qi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
SM Elbashir et al.
NATURE (2001)
Cooperative enhancement of specificity in a lattice of T cell receptors
C Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A comprehensive two-hybrid analysis to explore the yeast protein interactome
T Ito et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Calculations show substantial serial engagement of T cell receptors
C Wofsy et al.
BIOPHYSICAL JOURNAL (2001)
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
A Levchenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Electrostatic axially harmonic orbital trapping: A high-performance technique of mass analysis
A Makarov
ANALYTICAL CHEMISTRY (2000)
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
P Uetz et al.
NATURE (2000)
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
AA Alizadeh et al.
NATURE (2000)
Electron capture dissociation for structural characterization of multiply charged protein cations
RA Zubarev et al.
ANALYTICAL CHEMISTRY (2000)