Related references
Note: Only part of the references are listed.Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Jason D. Fontenot et al.
JOURNAL OF IMMUNOLOGY (2017)
Regulatory T Cells in the Control of Host-Microorganism Interactions
Yasmine Belkaid et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
Seth L. Masters et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Raphael Kopan et al.
CELL (2009)
Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency
Tuba Turul et al.
EUROPEAN JOURNAL OF PEDIATRICS (2009)
Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells
Gang Wei et al.
IMMUNITY (2009)
Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein
Li-Fan Lu et al.
IMMUNITY (2009)
The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
Di Yu et al.
IMMUNITY (2009)
CCCTC-Binding Factor and the Transcription Factor T-bet Orchestrate T Helper 1 Cell-Specific Structure and Function at the Interferon-γ Locus
Masayuki Sekimata et al.
IMMUNITY (2009)
Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells
Akihiko Kitoh et al.
IMMUNITY (2009)
Differential Expression of Interleukin-17A and-17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase
Julio Gomez-Rodriguez et al.
IMMUNITY (2009)
Professional Memory CD4+ T Lymphocytes Preferentially Reside and Rest in the Bone Marrow
Koji Tokoyoda et al.
IMMUNITY (2009)
Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
Yeonseok Chung et al.
IMMUNITY (2009)
Late Developmental Plasticity in the T Helper 17 Lineage
Yun Kyung Lee et al.
IMMUNITY (2009)
Regulation of Notch signaling during T- and B-cell development by O-fucose glycans
Pamela Stanley et al.
IMMUNOLOGICAL REVIEWS (2009)
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
Hiroaki Takatori et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells
Marc Veldhoen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Down-regulation of Gfi-1 expression by TGF-β is important for differentiation of Th17 and CD103+ inducible regulatory T cells
Jinfang Zhu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Runx proteins regulate Foxp3 expression
Ludovica Bruno et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
Fernando Cruz-Guilloty et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
T follicular helper cells differentiate from Th2 cells in response to helminth antigens
Arielle Glatman Zaretsky et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
Irah L. King et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells
Sven Klunker et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Dec2 Promotes Th2 Cell Differentiation by Enhancing IL-2R Signaling
Zhiduo Liu et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: Ikaros Is a Regulator of Th2 Cell Differentiation
Mary R. Quirion et al.
JOURNAL OF IMMUNOLOGY (2009)
Regulation of T Cell Activation by Notch Ligand, DLL4, Promotes IL-17 Production and Rorc Activation
Sumanta Mukherjee et al.
JOURNAL OF IMMUNOLOGY (2009)
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
Ye Zheng et al.
NATURE (2009)
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
Knut Woltjen et al.
NATURE (2009)
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
Aurelie T. Bauquet et al.
NATURE IMMUNOLOGY (2009)
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
Xuyu Zhou et al.
NATURE IMMUNOLOGY (2009)
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial T(H)2 lineage commitment
Xuexian O. Yang et al.
NATURE IMMUNOLOGY (2009)
Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells
Dipayan Rudra et al.
NATURE IMMUNOLOGY (2009)
Cytokine-secreting follicular T cells shape the antibody repertoire
R. Lee Reinhardt et al.
NATURE IMMUNOLOGY (2009)
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
Meghan A. Koch et al.
NATURE IMMUNOLOGY (2009)
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
Shlomo Z. Ben-Sasson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
Liying Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches
Masayuki Tsuji et al.
SCIENCE (2009)
Eos Mediates Foxp3-Dependent Gene Silencing in CD4+ Regulatory T Cells
Fan Pan et al.
SCIENCE (2009)
Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
Robert J. Johnston et al.
SCIENCE (2009)
Bcl6 Mediates the Development of T Follicular Helper Cells
Roza I. Nurieva et al.
SCIENCE (2009)
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
Ashutosh Chaudhry et al.
SCIENCE (2009)
Epigenetic control of T-helper-cell differentiation
Christopher B. Wilson et al.
NATURE REVIEWS IMMUNOLOGY (2009)
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
I-Cheng Ho et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Regulation and functions of blimp-1 in T and B lymphocytes
Gisliine Martins et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
T follicular helper (T-FH) cells in normal and dysregulated immune responses
Cecile King et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling
Xiaoqing Lu et al.
BLOOD (2008)
Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
Jeremy B. Samon et al.
BLOOD (2008)
Dynamic regulation of nucleosome positioning in the human genome
Dustin E. Schones et al.
CELL (2008)
High-resolution mapping and characterization of open chromatin across the genome
Alan P. Boyle et al.
CELL (2008)
IL-23 and IL-17 in tuberculosis
Shabaana A. Khader et al.
CYTOKINE (2008)
Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression
Sara A. Miller et al.
GENES & DEVELOPMENT (2008)
Signal Transducer and Activator of Transcription 4 Is Required for the Transcription Factor T-bet to Promote T Helper 1 Cell-Fate Determination
Vivian T. Thieu et al.
IMMUNITY (2008)
Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation
Min Shi et al.
IMMUNITY (2008)
A fundamental role for interleukin-21 in the generation of T follicular helper cells
Alexis Vogelzang et al.
IMMUNITY (2008)
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
Roza I. Nurieva et al.
IMMUNITY (2008)
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
Matthew A. Burchill et al.
IMMUNITY (2008)
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
Xuexian O. Yang et al.
IMMUNITY (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
Xuexian O. Yang et al.
IMMUNITY (2008)
Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells
Ludovic de Beaucoudrey et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Suppression of Th2 cell development by notch ligands Delta1 and Delta4
Jie Sun et al.
JOURNAL OF IMMUNOLOGY (2008)
Blimp-1 induced by IL-4 plays a critical role in suppressing IL-2 production in activated CD4 T cells
Lu Wang et al.
JOURNAL OF IMMUNOLOGY (2008)
Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells
Alusha A. Mamchak et al.
JOURNAL OF IMMUNOLOGY (2008)
Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses
Nisebita Sahu et al.
JOURNAL OF IMMUNOLOGY (2008)
Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bc16 gene expression
Luisa Cimmino et al.
JOURNAL OF IMMUNOLOGY (2008)
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
NATURE (2008)
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
Liang Zhou et al.
NATURE (2008)
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner et al.
NATURE (2008)
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
K. Venuprasad et al.
NATURE IMMUNOLOGY (2008)
Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells
Fuping Zhang et al.
NATURE IMMUNOLOGY (2008)
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
Marc Veldhoen et al.
NATURE IMMUNOLOGY (2008)
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor α-chain expression
Wei Liao et al.
NATURE IMMUNOLOGY (2008)
IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells
Valerie Dardalhon et al.
NATURE IMMUNOLOGY (2008)
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
NATURE IMMUNOLOGY (2008)
MicroRNAs: new regulators of immune cell development and function
David Baltimore et al.
NATURE IMMUNOLOGY (2008)
Notch and Presenilin Regulate Cellular Expansion and Cytokine Secretion but Cannot Instruct Th1/Th2 Fate Acquisition
Chin-Tong Ong et al.
PLOS ONE (2008)
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation
Nicholas van Panhuys et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin
Andrew M. Intlekofer et al.
SCIENCE (2008)
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
Yukiko Tone et al.
NATURE IMMUNOLOGY (2008)
The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and T(H)1 versus T-H-17 differentiation of CD4(+) T cells
Shin-ichi Kano et al.
NATURE IMMUNOLOGY (2008)
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
Lai Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ets-1 is a negative regulator of Th17 differentiation
Jacques Moisan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
STAT3 mutations in the hyper-IgE syndrome
Steven M. Holland et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Induction of FOXP3 expression in naive human CD4+FOXP3- T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
Dat Q. Tran et al.
BLOOD (2007)
An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity1
Timothy J. Harris et al.
JOURNAL OF IMMUNOLOGY (2007)
Autoantigen-specific TGFβ-Induced Foxp3+ regulatory T cells prevent Autoimmunity by inhibiting dendritic cells from activating autoreactive T cells
Richard J. DiPaolo et al.
JOURNAL OF IMMUNOLOGY (2007)
Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
Cesar Cobaleda et al.
NATURE (2007)
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells
Andrew M. Intlekofer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The development of inflammatory TH-17 cells requires interferon-regulatory factor 4
Anne Bruestle et al.
NATURE IMMUNOLOGY (2007)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Liang Zhou et al.
NATURE IMMUNOLOGY (2007)
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
Yoshiyuki Minegishi et al.
NATURE (2007)
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
Takeshi Egawa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
Yoshinori Naoe et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor
Nikhil S. Joshi et al.
IMMUNITY (2007)
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Thomas Korn et al.
NATURE (2007)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva et al.
NATURE (2007)
CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS
Dimitris Skokos et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-γ
Jamie R. Schoenborn et al.
NATURE IMMUNOLOGY (2007)
Direct regulation of Gata3 expression determines the T helper differentiation potential of notch
Derk Amsen et al.
IMMUNITY (2007)
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
Terry C. Fang et al.
IMMUNITY (2007)
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
Patricia A. Darrah et al.
NATURE MEDICINE (2007)
TH1 cells control themselves by producing interleukin-10
Anne O'Garra et al.
NATURE REVIEWS IMMUNOLOGY (2007)
TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
Ahjoku Amadi-Obi et al.
NATURE MEDICINE (2007)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
Nonredundant roles for Stat5a/b in directly regulating Foxp3
Zhengju Yao et al.
BLOOD (2007)
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome
Veronica Marrella et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
T cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
Ming O. Li et al.
IMMUNITY (2007)
Homeostatically proliferating CD4+ T cells are involved in the pathogenesis of an Omenn syndrome murine model
Khie Khiong et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Trawling for treasure: tales of T-bet
Laurie H. Glimcher
NATURE IMMUNOLOGY (2007)
Requirement of bic/microRNA-155 for normal immune function
Antony Rodriguez et al.
SCIENCE (2007)
Regulation of the germinal center response by microRNA-155
To-Ha Thai et al.
SCIENCE (2007)
Stat3 and Stat4 direct development of IL-17-secreting Th cells
Anubhav N. Mathur et al.
JOURNAL OF IMMUNOLOGY (2007)
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
Masahiro Ono et al.
NATURE (2007)
Cutting edge:: IL-2 is essential for TGF-β-mediated induction of Foxp3+ T regulatory cells
Todd S. Davidson et al.
JOURNAL OF IMMUNOLOGY (2007)
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
Xuexian O. Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
Askar M. Akimzhanov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
Luke M. Williams et al.
NATURE IMMUNOLOGY (2007)
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
Arian Laurence et al.
IMMUNITY (2007)
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
Yisong Y. Wan et al.
NATURE (2007)
Epigenetic control of the foxp3 locus in regulatory T cells
Stefan Floess et al.
PLOS BIOLOGY (2007)
Transcription factors T-bet and Runx3 cooperate to activate lfng and silence ll4 in T helper type 1 cells
Ivana M. Djuretic et al.
NATURE IMMUNOLOGY (2007)
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes
Amy A. Caudy et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease
Joshua D. Milner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
Matthew A. Burchill et al.
JOURNAL OF IMMUNOLOGY (2007)
Cutting edge: Regulatory T cells induce CD4(+)CD25(-)Foxp3(-) T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
LiLi Xu et al.
JOURNAL OF IMMUNOLOGY (2007)
Inborn errors of IL-12/23- and IFN-γ-mediated immunity:: molecular, cellular, and clinical features
Orchidee Filipe-Santos et al.
SEMINARS IN IMMUNOLOGY (2006)
Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion
Jinfang Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
GATA-3 regulates the development and function of invariant NKT cells
Peter J. Kim et al.
JOURNAL OF IMMUNOLOGY (2006)
A distal conserved sequence element controls Ifng gene expression by T cells and NK cells
Robin D. Hatton et al.
IMMUNITY (2006)
A role for Dicer in immune regulation
Bradley S. Cobb et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
IL-21 inhibits IFN-γ production in developing Th1 cells through the repression of eomesodermin expression
Akira Suto et al.
JOURNAL OF IMMUNOLOGY (2006)
Transforming growth factor-β controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms
Ming O. Li et al.
IMMUNITY (2006)
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-β receptor
Julien C. Marie et al.
IMMUNITY (2006)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
Zhi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Transforming growth factor-β induces development of the TH17 lineage
PR Mangan et al.
NATURE (2006)
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses
Masakatsu Yamashita et al.
IMMUNITY (2006)
T helper cell differentiation:: Regulation by cis elements and epigenetics
GR Lee et al.
IMMUNITY (2006)
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
T Usui et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
M Veldhoen et al.
IMMUNITY (2006)
Notch1 augments NF-κB activity by facilitating its nuclear retention
HM Shin et al.
EMBO JOURNAL (2006)
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors
JF Zhu et al.
CELL RESEARCH (2006)
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer et al.
NATURE IMMUNOLOGY (2005)
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
H Park et al.
NATURE IMMUNOLOGY (2005)
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
LE Harrington et al.
NATURE IMMUNOLOGY (2005)
Notch signaling is an important regulator of type 2 immunity
LL Tu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
H Yamane et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in TH1 cells
M Koyanagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway
M Yamashita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation
RA Corn et al.
JOURNAL OF IMMUNOLOGY (2005)
Aberrant T cell differentiation in the absence of Dicer
SA Muljo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13
LY Guo et al.
IMMUNITY (2005)
NFAT proteins: Key regulators of T-cell development and function
F Macian
NATURE REVIEWS IMMUNOLOGY (2005)
PU.1 expression delineates heterogeneity in primary Th2 cells
HC Chang et al.
IMMUNITY (2005)
The nervous system and innate immunity: the neuropeptide connection
KA Brogden et al.
NATURE IMMUNOLOGY (2005)
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
BS Cobb et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Stat5a inhibits IL-12-Induced Th1 cell differentiation through the induction of suppressor of cytokine signaling 3 expression
H Takatori et al.
JOURNAL OF IMMUNOLOGY (2005)
TEC-family kinases: Regulators of T-helper-cell differentiation
PL Schwartzberg et al.
NATURE REVIEWS IMMUNOLOGY (2005)
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
FA Scheeren et al.
NATURE IMMUNOLOGY (2005)
Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses
K Grenningloh et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Gfi-1 takes center stage in hematopoietic stem cells
ZJ Duan et al.
TRENDS IN MOLECULAR MEDICINE (2005)
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
ES Hwang et al.
SCIENCE (2005)
Hypersensitive site 7 of the T(H)2 locus control region is essential for expressing T(H)2 cytokine genes and for long-range intrachromosomal interactions
GR Lee et al.
NATURE IMMUNOLOGY (2005)
Cutting edge:: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
MC Fantini et al.
JOURNAL OF IMMUNOLOGY (2004)
Interleukin 2 plays a central role in Th2 differentiation
J Cote-Sierra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production
D Voehringer et al.
IMMUNITY (2004)
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
SY Pai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison
DU Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
GATA-3 in human T cell helper type 2 development
A Skapenko et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
TGF-β induces Foxp3+T-regulatory cells from CD4+CD25-precursors
S Fu et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
B Min et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Signaling through ltk promotes T helper 2 differentiation via negative regulation of T-bet
AT Miller et al.
IMMUNITY (2004)
Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity
KM Ansel et al.
NATURE IMMUNOLOGY (2004)
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
T Chtanova et al.
JOURNAL OF IMMUNOLOGY (2004)
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3
DU Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses
JF Zhu et al.
NATURE IMMUNOLOGY (2004)
STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis
LA Lieberman et al.
JOURNAL OF IMMUNOLOGY (2004)
IL-4-Induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation
N Seki et al.
JOURNAL OF IMMUNOLOGY (2004)
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
D Amsen et al.
CELL (2004)
Natural and induced CD4+CD25+ cells educate CD4+D25-cells to develop suppressive activity:: The role of IL-2, TGF-β, and IL-10
SG Zheng et al.
JOURNAL OF IMMUNOLOGY (2004)
Regulation of αβ/γδ, T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
K Tanigaki et al.
IMMUNITY (2004)
Divergent pro- and Antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
CA Murphy et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
A Blokzijl et al.
JOURNAL OF CELL BIOLOGY (2003)
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
EL Pearce et al.
SCIENCE (2003)
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells
Y Maekawa et al.
IMMUNITY (2003)
TCR-mediated Notch signaling regulates proliferation and IFN-γ production in peripheral T cells
T Palaga et al.
JOURNAL OF IMMUNOLOGY (2003)
Notch signaling augments T cell responsiveness by enhancing CD25 expression
SH Adler et al.
JOURNAL OF IMMUNOLOGY (2003)
Regulation of the Th2 cytokine locus by a locus control region
GR Lee et al.
IMMUNITY (2003)
Transcriptional regulation of Th2 differentiation by inducible costimulator
RI Nurieva et al.
IMMUNITY (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet
T Usui et al.
IMMUNITY (2003)
Inhibition of Th2 differentiation and GATA-3 expression by BCL-6
S Kusam et al.
JOURNAL OF IMMUNOLOGY (2003)
Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells
PJ Jorritsma et al.
JOURNAL OF IMMUNOLOGY (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
DJ Cua et al.
NATURE (2003)
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
S Aggarwal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
KW Makar et al.
NATURE IMMUNOLOGY (2003)
Stat5 activation plays a critical role in Th2 differentiation
JF Zhu et al.
IMMUNITY (2003)
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
G Trinchieri et al.
IMMUNITY (2003)
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
M Yamashita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines
ES Hwang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
M Lohoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
LY Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A 3′ enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
DC Solymar et al.
IMMUNITY (2002)
Gene silencing quantitatively controls the function of a developmental trans-activator
AS Hutchins et al.
MOLECULAR CELL (2002)
Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation
S Diehl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
M Afkarian et al.
NATURE IMMUNOLOGY (2002)
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation
JF Zhu et al.
IMMUNITY (2002)
T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC
D Haasch et al.
CELLULAR IMMUNOLOGY (2002)
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
J Rengarajan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
The potency of TCR signaling differentially regulates NFATc/p activity and early IL-4 transcription in naive CD4+ T cells
JL Brogdon et al.
JOURNAL OF IMMUNOLOGY (2002)
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
S Finotto et al.
SCIENCE (2002)
Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
SJ Szabo et al.
SCIENCE (2002)
NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naive T-H cells
J Rengarajan et al.
NATURE IMMUNOLOGY (2002)
Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription
Y Takeba et al.
JOURNAL OF IMMUNOLOGY (2002)
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
AA Lighvani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Mutation of Tec family kinase alters T helper cell differentiation
EM Schaeffer et al.
NATURE IMMUNOLOGY (2001)
The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3
H Kishikawa et al.
JOURNAL OF IMMUNOLOGY (2001)
Deletion of a coordinate regulator of type 2 cytokine expression in mice
M Mohrs et al.
NATURE IMMUNOLOGY (2001)
Regulation of interferon-γ gene expression by nuclear factor of activated T cells
A Kiani et al.
BLOOD (2001)
Impairment in the expression and activity of Fyn during differentiation of naive CD4+ T cells into the Th2 subset
T Tamura et al.
JOURNAL OF IMMUNOLOGY (2001)
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion
JF Zhu et al.
JOURNAL OF IMMUNOLOGY (2001)
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
AC Mullen et al.
SCIENCE (2001)
Stat5a regulates T helper cell differentiation by several distinct mechanisms
S Kagami et al.
BLOOD (2001)
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
JL Grogan et al.
IMMUNITY (2001)
IL-18-stimulated GADD45β required in cytokine-induced, but not TCR-induced, IFN-γ production
JF Yang et al.
NATURE IMMUNOLOGY (2001)
A critical role for NF-kappa B in Gata3 expression and T(H)2 differentiation in allergic airway inflammation
J Das et al.
NATURE IMMUNOLOGY (2001)
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
RS Wildin et al.
NATURE GENETICS (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
ME Brunkow et al.
NATURE GENETICS (2001)
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
NATURE GENETICS (2001)
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
D Breitfeld et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
B Oppmann et al.
IMMUNITY (2000)
Transient inhibition of interleukin 4 signaling by T cell receptor ligation
JF Zhu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
An intron transcriptional enhancer element regulates IL-4 gene locus accessibility in mast cells
JA Hural et al.
JOURNAL OF IMMUNOLOGY (2000)
Identification of STAT4-dependent and independent mechanisms of resistance to Toxoplasma gondii
GF Cai et al.
JOURNAL OF IMMUNOLOGY (2000)
GATA3 haplo-insufficiency causes human HDR syndrome
H Van Esch et al.
NATURE (2000)
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells
HJ Lee et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Requirement for RORγ in thymocyte survival and lymphoid organ development
ZM Sun et al.
SCIENCE (2000)
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
S Agarwal et al.
IMMUNITY (2000)
The role of Stat5a and Stat5b in signaling by IL-2 family cytokines
JX Lin et al.
ONCOGENE (2000)
A novel transcription factor, T-bet, directs Th1 lineage commitment
SJ Szabo et al.
CELL (2000)
Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile
D Jankovic et al.
JOURNAL OF IMMUNOLOGY (2000)
Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
DM Frucht et al.
JOURNAL OF IMMUNOLOGY (2000)
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
WJ Ouyang et al.
IMMUNITY (2000)
Stat6 regulation of in vivo IL-4 responses
FD Finkelman et al.
JOURNAL OF IMMUNOLOGY (2000)
Share Paper
