Journal
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 14
Volume 14, Issue -, Pages 491-513Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-genom-092010-110722
Keywords
risk communication; risk assessment; personalized medicine; genome-wide association; whole-genome sequencing
Categories
Funding
- NHGRI NIH HHS [R01 HG005092, R01HG005092, R01 HG002213, F32 HG006993, F32HG006993, U01HG006500, U01 HG006500, R01HG002213] Funding Source: Medline
- NIAMS NIH HHS [P60 AR047782, K24AR052403, P60AR047782, R01 AR049880, R01AR049880, K24 AR052403] Funding Source: Medline
- NIA NIH HHS [K24AG027841, K24 AG027841] Funding Source: Medline
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Communicating genetic risk information in ways that maximize understanding and promote health is increasingly important given the rapidly expanding availability and capabilities of genomic technologies. A well-developed literature on risk communication in general provides guidance for best practices, including presentation of information in multiple formats, attention to framing effects, use of graphics, sensitivity to the way numbers are presented, parsimony of information, attentiveness to emotions, and interactivity as part of the communication process. Challenges to communicating genetic risk information include deciding how best to tailor it, streamlining the process, deciding what information to disclose, accepting that communications may have limited influence, and understanding the impact of context. Meeting these challenges has great potential for empowering individuals to adopt healthier lifestyles and improve public health, but will require multidisciplinary approaches and collaboration.
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