Journal
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS
Volume 10, Issue -, Pages 333-354Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-genom-082908-150105
Keywords
sex chromosome evolution; pseudoautosomal regions; male mutation bias; dosage compensation; evolutionary strata
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Sex chromosomes have evolved multiple times in many taxi. The recent explosion in the availability of whole genome sequences from a variety of organisms mikes it possible to investigate sex chromosome evolution within and across genomes. Comparative genomic studies have shown that quite distant species may share fundamental properties of sex chromosome evolution, while very similar species can evolve unique sex chromosome systems. Furthermore, within-species genomic analyses can illuminate chromosome-wide sequence and expression polymorphisms. Here, we explore recent advances in the study of vertebrate sex chromosomes achieved using genomic analyses.
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