Journal
PHYTOCHEMISTRY
Volume 66, Issue 23, Pages 2771-2775Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2005.09.004
Keywords
endophytic fungus; Eupenicillium sp.; Glochidion ferdinandi; natural products; polyketides; phomoxin B; phomoxin C; eupenoxide; cyclic carbonate
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Chemical investigations of the culture broth from in endophytic fungus Eupenicillilim sp. have afforded two natural products phomoxins B (1) and C (2) as well as the previously reported fungal metabolite eupenoxide (3). Compounds 1 and 2 both contain a cyclic carbonate moiety that is rare among natural products. This paper reports the full spectroscopic characterisation of phomoxins B (1) and C (2) by NMR, UV, IR and MS data. All compounds were inactive against a panel of nosocomial microbes. (c) 2005 Elsevier Ltd. All rights reserved.
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