Journal
JOURNAL OF BIOMECHANICS
Volume 38, Issue 12, Pages 2460-2471Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2004.10.005
Keywords
heart valve; heart valve suture; finite elements; hyperelasticity
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The structural and functional effects of the edge-to-edge technique on the human mitral valve have been investigated, paying particular attention to the diastolic phase. An advanced finite element model of the valve has been developed, using a hyperelastic material schematization, suitable geometry and constraint conditions, and an effective fluidodynamic analysis. The edge-to-edge suture has been applied on this model and the diastolic phase has been simulated. The results of this calculation show that the operation increases the transvalvular pressure and the maximum stress in the leaflets, which reaches a level similar to that of the systolic phase. The influence of suture position and extension, and the mitral annulus dimension has also been investigated. The results indicate that a lateral location of the stitch is better than a central one, both regarding valve functionality (pressure level and mobility) and internal stresses level, that a longer suture worsens the valve functionality but reduces the stresses level, finally, that the dilatation of the mitral annulus does not affect the valve functionality but increases the stresses level. (c) 2004 Elsevier Ltd. All rights reserved.
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