Journal
PEDIATRIC HEMATOLOGY AND ONCOLOGY
Volume 22, Issue 8, Pages 699-703Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/08880010500278806
Keywords
allogeneic stem cell transplantation; alveolar rhabdomyosarcoma
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The authors report on 2 boys, 111/2 and 13 years old, who received allogeneic stem cell transplantation (alloSCT) from their HLA-identical sibling after relapse of stage IV alveolar rhabdomyosarcoma. Both patients were transplanted in a non-remission status. After alloSCT both patients experienced disease progression at the primary tumor location sites and died due to the underlying disease 146 and 379 days after transplantation. The authors conclude that an alloSCT derived graft versus tumor effect might not be effective enough to overcome alveolar rhabdomyosarcoma when transplantation is carried out in a nonremission status.
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