Journal
JOURNAL OF NATURAL PRODUCTS
Volume 68, Issue 12, Pages 1749-1753Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np050326r
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Eight new nornardosinane sequiterpenoids, laevinols A-H (1-8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6 beta-acetyl-4 beta,5 beta-dimethyl-1(10)alpha-epoxy-2 beta-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia laevis. Their structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
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