Journal
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30
Volume 30, Issue -, Pages 39-58Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-cellbio-100913-013325
Keywords
phase separation; P granules; chemical potential; biological liquids; origin of life
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Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
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