Journal
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
Volume 77, Issue 4, Pages 665-693Publisher
ACAD BRASILEIRA DE CIENCIAS
DOI: 10.1590/S0001-37652005000400008
Keywords
saliva; bites; hemostasis; host; vector; infection
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The saliva from blood-feeding arthropod vectors is enriched with molecules that display diverse functions that mediate a successful blood meal. They function not only as weapons against host's haemostatic, inflammatory and immune responses but also as important tools to pathogen establishment. Parasites, virus and bacteria taking advantage of vectors' armament have adapted to facilitate their entry in the host. Today, many salivary molecules have been identified and characterized as new targets to the development of future vaccines. Here we focus oil current information on vector's saliva and the molecules responsible to modify host's hemostasis and immune response, also regarding their role in disease transmission.
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