Journal
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Volume 29, Issue 8, Pages 639-647Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compmedimag.2005.06.002
Keywords
geometrical uncertainties; interobserver variability; organ motion; radiotherapy; stereology
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The Purpose of this study is to assess the uncertainties that arise in locating the boundaries of anatomical structures, such as the prostate and the bladder, due to interobserver variability in the delineation of the structures and to internal organ motion. The variabilities are computed ill all the radial directions and this information is used to obtain the margins, following the techniques and limitations imposed by medical practice. The margins obtained from the organ motions are significantly greater than those arising from interobserver variability. The developed tools, allow LIS to obtain the required margins ill all efficient way. (C) 2005 Elsevier Ltd. All rights reserved.
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