Type 1 diabetes mellitus: Etiology, presentation, and management

This article reviews our current understanding of the etiology, presentation, and management of type I diabetes. The discussion includes a review of the natural history of diabetes, the complex relationship between genetic and environmental risk for type I diabetes, and current methods for prediction of type I diabetes. The article also reviews the current management of children who have new-onset type I diabetes, age-appropriate management goals, and diabetes complications. Finally, the article discusses the future of diabetes screening programs and the progress toward the ultimate goal of curing type 1 diabetes.