4.5 Article Book Chapter

Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine

Journal

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY
Volume 1, Issue -, Pages 883-909

Publisher

ANNUAL REVIEWS
DOI: 10.1146/annurev.anchem.1.031207.112754

Keywords

Raman; CARS; molecular imaging; biomedical imaging; metabolic imaging; skin imaging

Funding

  1. Pfizer corporation
  2. National Institutes of Health [R01 GM62536-02]
  3. National Science Foundation [DBI-0649892, DBI-0138028]
  4. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM062536] Funding Source: NIH RePORTER

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Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging technique that is capable of real-time, nonperturbative examination of living cells and organisms based on molecular vibrational spectroscopy. Recent advances in detection schemes, understanding of contrast mechanisms, and developments of laser sources have enabled superb sensitivity high time resolution. such as Metabolite and drug imaging and tumor identification, raise many exciting new possibilities for biology and medicine.

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