Luteophanol D, new polyhydroxyl metabolite from marine dinoflagellate Amphidinium sp.

Luteophanol D ( 1), a new polyhydroxyl linear carbon-chain metabolite, has been isolated from the cultured marine dinoflagellate Amphidinium sp., which was isolated from Okinawan marine acoel flatworm Pseudaphanostoma luteocoloris. The structure of 1 was elucidated by detailed analyses of 2D NMR spectra. Luteophanol D ( 1) possesses two tetrahydropyran rings and twenty-three hydroxyl groups on C-63-linear aliphatic chain with one exo-methylene and two methyl branches.