Journal
THERAPEUTIC DRUG MONITORING
Volume 27, Issue 6, Pages 744-746Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.ftd.0000179849.42395.11
Keywords
nitric oxide synthase; asymmetric dimethylarginine
Funding
- Medical Research Council [MC_U120097118] Funding Source: Medline
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An increasing number of reports in the literature indicate that endogenously produced inhibitors of nitric oxide synthase (NOS), particularly asymmetric dimethylarginine (ADMA), regulate nitric oxide generation in disease states. This article describes the biology of ADMA and the implications for cardiovascular physiology and pathophysiology.
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