Journal
ANNALS OF VASCULAR SURGERY
Volume 24, Issue 3, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.avsg.2009.07.028
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Antithrombin is a potent inhibitor of the coagulation cascade exerting its primary effects on activated factors X, IX and II. It is the mechanism by which heparin and low-molecular weight heparin cause anti-coagulation. Deficiency of Antithrombin presents as a hypercoagulable state, and may result in unexplained deep venous thrombosis, arterial thrombosis and systemic embolization.
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