Journal
EXPERT OPINION ON PHARMACOTHERAPY
Volume 6, Issue 15, Pages 2691-2697Publisher
ASHLEY PUBLICATIONS LTD
DOI: 10.1517/14656566.6.15.2691
Keywords
migraine; motion sickness; serotonin; triptan; vertigo; vestibular
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Motion sickness commonly occurs after exposure to actual motion, such as car or amusement park rides, or virtual motion, such as panoramic movies. Motion sickness symptoms may be disabling, significantly limiting business, travel and leisure activities. Motion sickness occurs in similar to 50% of migraine sufferers. Understanding motion sickness in migraine patients may improve understanding of the physiology of both conditions. Recent literature suggests important relationships between the trigeminal system and vestibular nuclei that may have implications for both motion sickness and migraine Studies demonstrating an important relationship between serotonin receptors and motion sickness susceptibility in both rodents and humans suggest possible new motion sickness prevention therapies.
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