Journal
INFECTION AND IMMUNITY
Volume 73, Issue 12, Pages 8411-8417Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.73.12.8411-8417.2005
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Funding
- Biotechnology and Biological Sciences Research Council [BBS/E/I/00000715] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [BBS/E/I/00000715] Funding Source: Medline
- Wellcome Trust [OZ0707] Funding Source: Medline
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Intestinal colonization by enteropathogenic and enterohemorrhagic Escherichia coli requires the locus of enterocyte effacement-encoded type III secretion system. We report that NleC and NleD are translocated into host cells via this system. Deletion mutants induced attaching and effacing lesions in vitro, while infection of calves or lambs showed that neither gene was required for colonization.
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